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Serum samples were received from 123 veterinarians in South Africa and 4 from neighboring countries.
During 2003 2006, a total of 3,833 serum samples were received from hospitals and clinics.
Serum samples were received separately in red-topped tubes and kept at –20°C until antibody analysis was performed.
One hundred and one consecutive neonatal serum samples were received from a tertiary hospital for 25OHD analysis.
Serum samples were received at IPM from 134 persons with suspected cases who lived in 16 districts: 36 cases were confirmed, and 31 were considered probable.
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These serum samples were collected after receiving individuals' informed consent under approval of the Institutional Review Board Control.
The other 6 patients with an indication for prophylaxis for whom follow-up serum samples were available did not receive prophylaxis because the indication for prophylaxis was not recognized by the treating physician.
A potential limitation to this study is that 07/150 was derived from recipients of adjuvanted whole-virus vaccine but test serum samples were obtained from persons who received plain or adjuvanted split-product vaccines.
Serum samples were obtained from breast cancer patients receiving adjuvant treatment or chemotherapy for metastasised disease at the Department of Oncology/ Hematologyat the University Medical Center Hamburg-Eppendorf.
Yellow fever (YF)– and Japanese encephalitis (JE antibody positive human serum samples were obtained from healthy adult donors who received vaccines against YF virus (YF-VAX®) or JE virus (JE-VAX™), respectively.
Between August 2008 and August 2011, pretreatment serum samples were obtained from KRAS wild-type (WT) patients who received anti-EGFR antibody treatment.
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