To predict 5-year OS probability, six prognostic variables are used: age at surgery, preoperative platelet count (10 l−1), tumour grade (1 2 vs 3), histology (serous vs non-serous), presence of ascites and residual disease status (0 vs<0.5 1.00.5–1.0 vs 1 2 vs >2 cm).
On multivariate analysis controlling for FIGO stage and high-grade serous carcinoma, the presence of LVSI remained a statistically significant variable for progression-free survival (HR: 2.06, 95% CI: 1.01 4.24, P = 0.048, Table 3).
After controlling for high-grade serous carcinoma, the presence of LVSI showed a trend toward increased risk of poor progression-free survival (HR: 4.09, 95% CI: 0.75 22.4, P = 0.10).
We found that the significant (P≤ 0.05) prognostic factors for overall survival were age at diagnosis, FIGO stage, grade of tumour, histology (mixed mesodermal, clear cell and endometrioid versus serous papillary), the presence or absence of ascites, albumin, alkaline phosphatase, performance status on the ZUBROD-ECOG-WHO scale, and debulking of the tumour.
This finding is supported by our observation of similar high amounts of NAA found in hydrosalpingeal fluid, which is a fluid accumulation in the fallopian tube due to distal obstruction.[12] However, the question remains why NAA is found in such high amounts in oCF of serous EOT as its presence and function have been specifically been assigned to the human brain.
Conjunctival hyperemia, moderate serous epiphora, buphthalmia and presence of an intraocular mass were detected in the left eye.
High KLK6 mRNA expression was associated with the presence of serous ovarian cancer and late stage disease.
Group B (11 eyes) was initiated with endolaser treatment regimen due to the presence of serous retinal detachment.
The presence of serous retinal detachment in eyes with uveitic macular edema does not appear to worsen visual prognosis.
The presence of serous macular detachment, which may also be a predictive factor for ranibizumab treatment outcome [ 26], was assessed using baseline OCT images of the fovea.
Cell blocks were obtained from all 15 USC cell lines and reviewed by a gynecologic surgical pathologist to confirm the presence of serous carcinoma cells.
