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I wanted to be theatrical, but I am very serous about what I do".
Recent data demonstrated a doubled risk also for low-grade serous ovarian cancers (about 5% of ovarian cancers) while mucinous (about 5%) and high-grade serous (about 60%) cancers appear not to be associated with the disease.
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We report concordance between FS and definitive histology in 60.2% of the cases (over 70% for serous and about 50% for mucinous histotypes).
Summer is over, so it is time to get serous and talk about sheep and opera.
There was about 1300 ml of serous pleural effusion, which was no malignant.
The highly lethal serous histological type comprises about two-thirds of cases and causes most disease-related deaths.
Mutation of p53 is common in high grade ovarian serous carcinomas, occurring in about 80% of cases based on the literature [33] and in the current series (85%), while low grade ovarian serous carcinomas and serous borderline tumors typically do not possess p53 mutation [6], [53].
The serous histotype accounts for about 80% of EOCs, and the majority show an inactivating mutation of the tumor suppressor gene TP53.
Ovarian cancers with serous histology account for about two-thirds of the incident disease and these cases usually present at an advanced stage leading to a very high mortality rate.
Serous epithelial carcinoma accounts for about 70% of EOC and is often associated with peritoneal metastases and poor survival [13].
Uterine serous tumours, which accounts for about 10% of endometrial cancers, have a higher propensity for lymphovascular invasion, and intraperitoneal as well as extra-abdominal spread, than endometrioid carcinoma.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com