Exact(3)
While 16 of 24 (66.6%) eyes with PED (15 fibrovascular 1 serous PED) showed partial improvement in PED height, 2 (8.3%) eyes with PED (1 serous, 1 fibrovascular) showed complete resolution after aflibercept treatment.
Four ERBB2 amplified samples (1 serous, 1 mucinous, 1 mucinous borderline, and 1 clear cell) were expressed correspondingly higher than the 3 serous samples with deleted ERBB2 (p=0.06, Wilcoxon).
On the other hand, of the 24 eyes with PED, 2 eyes (8.3%) (1 serous, 1 fibrovascular) had complete resolution, 16 eyes (66.6%) had partial improvement of PED, 4 eyes (16.6%) remained stable, while 2 cases (8.3%) had an increase in PED height (Table 2).
Similar(57)
For instance, choroidal thickness increases in hyperopia [24], acute VKH [14, 15, 18], central serous chorioretinopathy [27, 28], and polypoid choroidal vasculopathy [29, 30].
This also occurred in 20 of 84 (24%) G3 cancers (6 serous cancers, 7 carcinosarcomas and 7 clear cell carcinomas).
The 6 cases of benign tumours with SLP-2 overexpression included 5 serous and 1 mucinous type; The 9 cases of borderline ovarian tumour with SLP-2 overexpression included 6 serous tumour, 2 mucinous tumour, and 1 mixed tumour.
Histologically, there were 20 serous, 5 endometrioid, 6 mucinous, 5 clear cell, and 13 undifferentiated OVCA.
Histopathological diagnosis of the remaining 69 EOTs revealed 36 serous, 23 mucinous, 8 endometrioid and 2 clear cell tumors.
The 111 informative ovarian carcinomas in tissue microarray used in this study consist of 82 serous, 12 mucinous, 12 clear cell, and 5 endometrioid subtypes (Table 1).
The majority of ovarian cancers were of high grade (grade 1 (5), grade 2 (18), grade 3 (56)) and serous in histology (serous (65), endometrioid (4), mucinous (3), undifferentiated (2), mixed (1), clear cell (1), unclassified (3)).
The subtype distribution was representative of the US population, with a larger proportion of serous (42%) and endometrioid (26%) carcinoma (Table 1).
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