Exact(1)
As we discuss below, serotype diversification can convert relatively avirulent serotypes to highly virulent ones.
Similar(57)
On the basis of the molecular clock and other assumptions made in the Bayesian analysis, the number of lineages of S. enterica Enteritidis is estimated to have increased sharply during 1925 1950 ce, which indicated rapid diversification of serotype Enteritidis.
Several events appear to have contributed to the diversification of the M1 GAS serotype, leading to the emergence of the M1T1 global strain.
The heterogeneous distribution of mobile elements has impacted the diversification of O26:H11 more than other EHEC 2 serotypes.
Whole genome sequencing allows a more precise reconstruction of the emergence and diversification of the PMEN14 clade than afforded by MLST and serotyping.
Taking into account the extensive, uncontrolled movement of animals across the borders and the ease of virus spread and infection of multiple serotypes in one animal, the role of recombination events in the genetic diversification of FMDV cannot be excluded.
We believe that the unique features of the newly emerged subclones of GAS serotypes, in particular the M1T1 clonal strain, evolved as a result of diversification of the bacteria and acquisition of new genes that improved their fitness to infect humans.
While genes with evidence of positive selection identified here may provide promising targets for future mutational studies aimed at further identifying mechanisms that contribute to Salmonella diversification, including its adaptation to specific host species, one cannot extrapolate our findings on a few Salmonella serotypes to other serotypes unless additional analyses are performed.
Diversification helps.
Diversification specialist?
Their aim is diversification.
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