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The aim of this study was to design the best serologic strategy for diagnosing human alveolar echinococcosis (AE) cases in medical laboratory routine procedures.
Specific serology such as IgA-TG2 and IgG-DGP with or without a strategy for determination of total IgA level should be the preferred serologic strategy for detection of CD.
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Our approach of using NAT yield data to project WNV infections has advantages over serologic strategies.
Because most pregnant women receive their diagnosis during the chronic, asymptomatic stage of Chagas disease, screening with 2 sequential serologic tests is the most efficient strategy for detection of infection (12 ).
Although guidelines developed by national professional organizations for the management of CAP were available during the study period (11 – 13 ), these guidelines did not directly address the best strategy for Coccidioides spp. serologic testing (11 – 11 ).
We propose a new, accurate, and cost-sparing 2-step strategy for screening, based on selection of the individuals with potential CD by HLA-DQ typing and on longitudinal serologic CD screening in this selected group.
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