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"seriously disrupt" is correct and can be used in written English.
You can use this phrase to describe a situation where there is a significant disturbance or interruption in the usual flow of something. For example: "The storm seriously disrupted my plans for the day."
Exact(59)
Critics wondered whether it would seriously disrupt the hit-and-run guerrilla insurgency of Boko Haram.
There are concerns that the plans could seriously disrupt the flamingo activities there.
Large-scale social unrest could seriously disrupt China's auto industry and economy as a whole.
Such a move would seriously disrupt reorganization plans already approved in bankruptcy proceedings.
The authorities said the sheer number of arrests would seriously disrupt the cartel's distribution system.
And the ISI could, if it wanted to, seriously disrupt their activities.
Of course, illness, both mental and physical, can seriously disrupt a healthy libido at any age.
A letter signed by 82 House Republicans says it "would seriously disrupt financing of Medicaid programs around the country".
"Imposing haircuts on private investors can seriously disrupt the financial and real economy of both the debtor and creditor countries," he said.
Though it eventually stamped out this heresy, the harsh response of the Inquisition, beginning in the 1230s, apparently did not seriously disrupt urban or rural prosperity.
A veto would be recommended if the bill "contains provisions that would seriously disrupt the F-35 program," the administration said.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com