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In our series, RRD occurred in 3.1% of patients with uveitis, constituting a serious uveitis complication that was responsible for a final VA of ≤ 20/200 in 12 (41%) of the 29 eyes affected with uveitic RRD.
Serious ocular AEs were attributable either to the injection procedure (presumed endophthalmitis) or to ranibizumab (serious uveitis) (Rosenfeld et al. 2006a).
All patients in both trials received intravitreal injections, but serious uveitis occurred in only 7 of the 1,139 patients (0.6%)[ 2, 3] Including this very rare event in the model would not impact predicted health or cost outcomes.
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To identify risk factors for a severe uveitis course among children with noninfectious uveitis.
Supplemental therapy with other immunomodulatory agents is often necessary to control serious manifestations such as uveitis and meningoencephalitis and to reduce the incidence of long-term steroid toxicity.
Steroids and immunosuppressive drugs are currently the only therapeutics for uveitis and have serious ocular and systemic toxicities.
In our study severe form of uveitis was dominant (71.1%).
Main causes of serious vision loss in Behçet's uveitis include optic nerve atrophy, macular damage, and retinal vascular occlusions causing ischemic retinopathy with neovascularization, vitreous hemorrhage, or neovascular glaucoma [1, 2, 5, 6].
11, 12 Serious ocular adverse events included endophthalmitis, uveitis, vitreous hemorrhage, rhegmatogenous retinal detachment, retinal tear, or lens damage.
Behçet's disease (BD) is a serious sight-threatening clinical entity of uveitis that can be accompanied by recurrent oral aphthous ulcers, genital ulcers, and skin lesions.
Equine recurrent uveitis (ERU) is the most serious eye disease in horses worldwide.
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CEO of Professional Science Editing for Scientists @ prosciediting.com