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His peaks include six champion jockey's titles and a long list of major races but there have been some serious troughs along the way, some of which would have been easily avoided by another man.
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Africa, Asia and Latin America have stood still or have seen short-lived peaks followed by serious financial troughs.
But, he said, baseball's word not only is not its bond, but its motivation is not to help McCourt and the Dodgers through a serious financial trough.
This is comparable to the Mw 7.9 of the 1923 Kanto earthquake (Kanamori, 1977) that occurred at the Sagami Trough causing serious damage in the metropolitan area.
The strong and prolonged shaking of the long-period ground motions that could be generated by future great megathrust earthquakes along the Nankai Trough could cause serious damage to modern large-scale construction in the Tokyo region.
The troughs have seen rain producing serious floods in central and eastern Europe and catastrophic ones in Pakistan.
These shortcomings result in serious distortion, especially around peaks and troughs in the signal (Chengming et al. 2014; Ivan et al. 2005).
Recent clinical practice guidelines of the Infectious Diseases Society of America IDSAA) recommend a loading dose of up to 25-30 mg/kg to achieve target trough concentrations rapidly in serious MRSA infections, including pneumonia and bacteremia [22].
Recent clinical practice guidelines of the Infectious Diseases Society of America (IDSA) recommend a loading dose of up to 25-30 mg/kg to achieve target trough concentrations rapidly in serious MRSA infections, including pneumonia and bacteremia [ 22].
However maintenance of higher trough concentration is often required in serious methicillin-resistant Staphylococcus aureus infections because of the high minimum inhibitory concentration.
There was a greater incidence of serious AEs and renal AEs as the vancomycin trough level increased (p = 0.03 and p < 0.01, respectively) (Table 2).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com