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Erdmann et al. [4] demonstrated a significant reduction of pain, associated morbidity and convalescent time in intra-articular fractures of the calcis, a serious subset of trauma to the lower limb.
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The incidence rate for hospitalized infections (a subset of serious) in the DB periods of the RCTs was also increased however again not significant: 3.05/100 py for abatacept and 2.15/100 py for placebo (rate ratio 1.42; 95% CI: 0.82 to 2.45).
Similarly, the incidence rates of infections requiring hospitalization (a subset of serious infections) in the combined double-blind placebo-controlled trials was 3.05/100 py and 2.16/100 py for abatacept and placebo, respectively [ 14].
On the other hand, the 3 to 4-fold reduction in the rate of translation, and the narrowed range of translational efficiencies evoked by depletion of eIF4G, could have serious consequences for a subset of dosage-sensitive proteins with essential functions in the cell.
PLE is a serious complication in a subset of patients with Fontan circulation It is unclear what triggers the development of PLE and why it can develop so long after Fontan surgery PLE may be the common endpoint of multiple pathophysiological pathways.
The current analysis focused on a subset of 379 serious infection events with ICD-9 discharge diagnoses available for review.
Separate analyses were done to analyze environmental effects on more serious cases by limiting the subset of counts to those for which the visits resulted in hospital admissions.
Although most patients with HCM are asymptomatic, serious consequences are experienced in a subset of affected individuals who present initially with sudden cardiac death or progress to refractory heart failure.
In contrast to the success of CD152-Ig in murine studies, the humanized CD152-IgG1 fusion protein abatacept has been disappointing in the clinic due to an increase in serious adverse events found in a subset of patients in a phase IIb study [ 25].
Since drug-related and serious clinical adverse events are a subset of all adverse events and reported less frequently, these events were summarized using a lower cut point (i.e., an incidence rate of at least 0.2 incident events per 100 patient-years).
47 Canal serves as a kind of downtown clubhouse for a certain subset of young but smart, stylish but serious artists.
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