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"serious struggle" is correct and usable in written English.
You can use it to describe an intense and difficult ordeal or challenge. For example, "The family was going through a serious struggle to make ends meet."
Exact(24)
Stopping it will require a serious struggle by the environmental movement.
But for a labor of love, this one's a serious struggle.
What one has to do to get out of poverty is not a romantic little journey, but a serious struggle".
Mastering conjugations was a serious struggle for me, almost a dialectical critique of the metaphysics of grammar.
'It has been a very serious struggle," says Nile Rodgers of Chic, when asked how he is doing.
The Republicans, for all their faults, at least seem set for a serious struggle that will see some critical issues debated and perhaps define their future.
Similar(36)
"Those in power have many serious struggles ahead," Aghajari predicted.
Many of the brains that were donated for study came from ex-players who either died of unnatural circumstances or had serious struggles like Junior Seau and Dave Duerson.
DACHER KELTNER Yeah, that's amazing, and I like your word "released". And what we know about the physiology of laughter is that it, you know, life has these serious struggles and conflicts and hard work.
Though Activision has had serious struggles at times, analysts tend to give high marks to Mr. Kotick, the longest-running chief executive among the major game companies and an inveterate businessman.
While parents may have promoted their "modernness" to me or took pride in it to justify the transnational relationship with their child, there could be more serious struggles between the "more modern individual" and conservative social norms in the local community.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com