Sentence examples for serious specificity from inspiring English sources

For GPCRs, serious specificity concerns have been raised in a number of articles contesting the reliability of many GPCR antibodies for IHC (e.g., [224]).

The sensitivity of conventional methods is high, but there are serious limitations in specificity.

While these minor differences could be used to inform specialized CPD packages, the similarity of training needs across all subsamples might support a standardized set of modules that could be delivered to all midwives, without serious loss of specificity or additional expenditure incurred by setting up separate courses.

None of this has the hard-earned specificity of serious scholarship, but instead feels fuzzily atmospheric and impressionistic.

This study lends weight to the argument that both universality as well as cultural specificity characterizes serious suicidal expressions as suggested by several researchers [ 37].

Comparison of the assays' performance in terms of sensitivity and specificity raises serious questions as to their reliability for identification of infected individuals in the field.

Although SA-β-Gal staining has gained broad acceptance as a marker of senescence, its usage in various aspects of aging research has generated serious doubts about its specificity.

However, the results showed serious compromise of the specificity of the SIT in vaccinated animals prior to challenge (4 of 4 false-positive reactors), which completely disappeared when using the CIT.

A large unexplained "technical" noise component in the experimental measurements and its non-uniform location in the genome are serious limitations for the specificity of the current ChIP-based methods [ 7, 9, 11- 13].

Taken together, the demonstration that GlyH-101 inhibits VSORC and CaCC at almost the same concentrations (5 10 µM) as used to fully inhibit CFTR, raises serious questions about its specificity and excludes this compound from future investigations as a means of clearly distinguishing CFTR-mediated conductance in a multicomponent Cl− channel conductance analysis.

Obviously such changes could further affect host and tissue specificity, potentially having serious consequences.