In India the company suffered a serious setback when it resolved, under the inspiration of Sir Josiah Child, to resort to armed trade and to attack the Mughals.
In January, the government suffered a serious setback when councils in Cumbria rejected a proposal to host a deep geological disposal site.
Last year, the polio eradication program suffered a serious setback when cases globally rose to 1,918 because of a large outbreak in Uttar Pradesh in India.
Last week it faced a serious setback when plans for a share buyback that would have given investors £3.4bn in return for 25percentnt of their holdings were put off.
In March, Britain's nuclear program suffered a serious setback when two German companies, RWE and E.On, announced that they would not proceed with a £15 billion joint venture in Gloucester.
In March 2016, about three months after the transplant, Lucy suffered a serious setback when her right lung collapsed as a result of pneumonia, and she underwent surgery at Children's National Medical Center.
Gene therapy suffered a serious setback when authorities in France and the United States announced that the field's first and only successful experiment may have given a 3-year-old boy an illness similar to leukemia.
Once considered a front-runner in the mayor's race, Mr. Weiner was dealt a serious setback when Mr. Bloomberg re-engineered the city's term limits so he could seek re-election.
In March, Britain's nuclear program suffered a serious setback when two German companies, RWE and E.On, announced they would not proceed with a £15 billion, or roughly $24 billion, joint venture in Gloucester, blaming the economic crisis and arguing that the German government's plan to phase out nuclear power had put additional pressure on their balance sheets.
Munster's hopes of reaching the Pro12 play-offs suffered a serious setback when they were resoundingly beaten by Treviso at the Stadio di Monigo.
