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As a result of this week's developments, serious progress has been made.
His commitment to turning the Maldives into the world's first carbon-neutral country was typically ambitious, and – although all bets are now off – serious progress has already been made.
Update 11/18: ABC News is reporting that "serious progress" has been made on the possible appointment of Hillary Clinton as Secretary of State.
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Kerry had expressed confidence on Friday that there was a framework for a ceasefire agreement which could ultimately succeed, saying "serious progress" had been made, although he admitted there was more work to do.
Speaking in Cairo on Friday, Kerry said he was confident there was a framework for a ceasefire agreement that would ultimately succeed and that "serious progress" had been made, although there was more work to do.
The lead negotiators, the US secretary of state, John Kerry, and the Iranian foreign minister, Mohammad Javad Zarif, emerged from the talks claiming that serious progress had been made and an accord was possible within the time allowed.
"Good progress has been made," he continued, "but the issues are still overwhelmingly serious and complicated and sad".
The absence of serious progress this year has sown new doubts, here and abroad, that Mr. Obama will be able to reach even the scaled-down goals he set for America's mission in the time he laid out in his speech at West Point seven months ago.
Applying simple goals as a planning framework for resource allocation and as a definition of human progress has serious consequences.
Each of these approaches has serious limitations, and significant progress has only been made by combinations of more than one.
However, recently the situation has changed dramatically and metabolic diseases have received serious attention and considerable progress has been made in prevention and therapeutic management.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com