Sentence examples for serious mutation from inspiring English sources

Usually, these men have two CFTR mutations: one CF-causing (hence serious) mutation, which in homozygosity or a compound heterozygous status would lead to the classical form of CF, and one 'mild' mutation or variant in trans.

There are many serious mutations among insects due to the absence of public conveniences.

Since all the children whose data Dr Jacquemont examined had been diagnosed with problems, if the girls had more serious mutations than the boys did, that suggests other aspects of their physiology were covering up the consequences.

Usually patients have less serious mutations: a single front tooth or a slightly deformed face.

However, NPD does not differentiate between those with severe CFTR mutations from other CF patients with minor but serious mutations.

Mutations producing enzymes retaining 20 to 60% of normal activity are associated with NCAH, while more serious mutations resulting in totally ablate enzyme activity or 1 2% of normal activity, are associated with classic disease.

As well, we advocate a process whereby investigators retain some latitude with respect to the most serious, potentially life-threatening mutations.

Mutation of TTBK2 may potentially be more serious than mutations of other proteins involved in ciliopathies because its heterozygous mutation results in SCA at the age as early as of 11 years old [ 22].

Scientists for the first time have successfully edited genes in human embryos to repair a common and serious disease-causing mutation...

BRCA1 is part of a complex that repairs double-strand breaks in DNA [ 51]; the overexpression of BRCA1 may suggest that DNA damage is serious; but BRCA1 mutation carriers are at an increased risk of prostate and breast cancer [ 52].

In murine systems, the most serious consequences of mutations of the TAM genes involve the immune system.