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Even in this subgroup, most trials were small with limited statistical power and serious methodological limitations.
All studies had serious methodological limitations.
Most studies have serious methodological limitations.
One study had serious methodological limitations due to high risk of attrition bias [37].
Serious methodological limitations were judged to exist when a non-randomized study collected less than 17 points on the checklist.
Acupuncture has been studied as an alternative therapy for controlling blood pressure (BP) but previous studies have serious methodological limitations.
Similar(47)
Research on this topic has serious methodological and theoretical limitations and biases.
A high risk of bias due to absence of blinding of patients and personnel remains a serious methodological challenge for acupressure trials and poses a main limitation to presented results.
There is also a serious methodological issue.
There will be some serious methodological challenges to doing that, of course.
It is true that this approach, too, comes with serious methodological caveats, such as verifiability, selection bias or observer bias.
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