Sentence examples for serious limitations such from inspiring English sources
However, most of these systems face several serious limitations such as limited flexibility, zero extensibility, and the ad hoc nature of their components.
Nevertheless, synthesis and application of Ge nanomaterials have suffered from serious limitations such as some stiff experimental conditions, high temperatures, toxic precursors, and complex synthesis process [8].
Reliance on various diversification strategies and traditional risk sharing among kin and families has serious limitations, such as the problem of covariate risk within such networks.
G-TwYST replicates many of the features of Séralini et al. [2, 3], but has serious limitations, such as using NK603 maize that has been sprayed only once with Roundup.
Notwithstanding the fact that this methodology has serious limitations (such as the loss of spatial information), it is broadly applicable across different cancer types.
Although BMS have excellent mechanical characteristics, they failed because of serious limitations such as stent thrombosis which requires prolonged antiplatelet therapy and mismatch of the stent to the vessel size.
Unfortunately, many of the studies have serious methodological limitations, such as having few included participants or high drop-out rates resulting in low statistical power [ 14, 15, 17, 20].
However, despite the serious limitations in using such low significance sequence similarity scores for prediction of functional properties, other evidence exists to suggest that this is a useful representation of the GPCR superfamily.
The fixed control signals and the relatively broad dead-bands required for stabilization of this type of controller impose serious limitations on the performance of such systems.
Such trials have serious limitations that put the findings in question and therefore inhibit evidence-based QI.
There are also serious limitations for the existing invasive biomarkers, such as those used in FibroTest-ActiTest, AST/ALT and AST/platelets ratio index (APRI).
