Sentence examples for serious issue when from inspiring English sources

"It's a serious issue when you're dealing with advertisers," he said.

The critics agree that contamination can be a serious issue when using polymerase chain reaction technology.

This would project a serious issue when other universities in the region have proven to be more attractive, in terms of student's achievement, tuition fee and personalized assistance.

Since the surfactants invariably present residual surfactants or organic additives attached to the surfaces of products can block the active sites, it is a serious issue when considering applications in gas sensing or catalysis.

This article describes the various problems drivers have with heat – I never thought about it, but dehydration and heat exhaustion can be a serious issue when you're driving a hot car in the sun for several hours while wearing protective gear, a helmet, and so on.

For residents and activists, it's a serious issue when the city's poorest, including children, are made to live without running water in their home.

Catalytic electrode poisoning is one of the most serious issues when noble metals are involved.

In the past few years, consoles have had some serious issues when they first launch, and the PlayStation 3 is no different.

This conservative sequencing strategy ensured accuracy and prevented erroneous base calls associated with sequencing error that can cause serious issues when only single sequences are analyzed.

Amanda Capes-Davis, based in Sydney, Australia, and chair of the International Cell Line Authentication Committee, agrees that mislabeling of cell samples in transcriptomic studies is a serious issue, particularly when using so-called cell lines, which have been grown in lab dishes for extended periods, even years to decades.

However, a serious issue arises when RhB is used for polymer-based devices such as poly(dimethylsiloxane) (PDMS), commonly used for microfluidic applications.