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Although a serious human pathogen many of the virulence mechanisms of B. pseudomallei remain to be elucidated.
Having such an inbred mouse model for the study of MPXV could greatly increase our wealth of knowledge about this serious human pathogen.
The most serious human pathogen among the tickborne viruses in the African region is Crimean-Congo hemorrhagic fever virus (CCHFV), a member of the Nairovirus genus that can cause fatal hemorrhagic disease (8, 9 ).
Enterohemorrhagic Escherichia coli O157 H7 is a serious human pathogen that is responsible for many food-borne epidemic outbreaks, and the infection of E. coli O157 H7 can cause bloody diarrhea, hemorrhagic colitis and the hemolytic uremic syndrome [ 1, 2].
To insert a substantial amount of recoverable viral particles into the sample collection system, a person trying to deceive the system would have to engineer and grow these viruses an act sufficiently close to actual bioterrorist use that it requires detection, whether the agent is a serious human pathogen or not.
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Because bats can harbor serious human pathogens, including rabies viruses, the researchers worked with the tissues in a biosafety level (BSL -2 plus facility with containment caBSL -2 and restricted access.
Arenaviridae, Bunyaviridae, and Orthomyxoviridae, the principal families of segmented negative single-stranded RNA viruses (sNSV), each include serious human pathogens such as Lassa fever, Crimean-Congo haemorrhagic fever, and influenza viruses, respectively.
The genus Corynebacterium includes Gram-positive microorganisms of great biotechnologically importance, such as Corynebacterium glutamicum and Corynebacterium efficiens, as well as serious human pathogens, such as Corynebacterium diphtheriae and Corynebacterium jeikeium.
Enterohemorrhagic Escherichia coli (EHEC; also variously referred to as Verocytotoxin producing E. coli, VTEC and Shiga toxin producing E. coli, STEC), serotype O157∶H7 is a serious human enteric pathogen, as evidenced by an outbreak across North America due to the ingestion of contaminated spinach [1].
To characterize further the roles of the different C-terminal components of the gp38 adhesins in receptor-binding specificity, we focused on a subset of the T4-type phages whose adhesins have a dual recognition specificity that allows them to infect both E. coli and Y. pseudotuberculosis, a serious human and animal pathogen (Naktin and Beavis 1999).
Enterohemorrhagic Escherichia coli (EHEC), a serious food and waterborne human pathogen, is well equipped with an arsenal of molecular factors that allows it to survive passage through the gastrointestinal tract and successfully colonize the large intestine.
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