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Yet another serious difficulty faced by originalism is one alluded to above: contemporary life is often very different from the life contemplated by those who lived at the time of the constitution's adoption.
However, the potentially serious difficulty faced by these scenarios is that prokaryotes have no known mechanisms for engulfing other prokaryotic cells (although at least one case of endosymbiosis among bacteria has been reported [ 14]).
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The most serious difficulty facing Darwin's evolutionary theory was the lack of an adequate theory of inheritance that would account for the preservation through the generations of the variations on which natural selection was supposed to act.
Of particular concern is the continuing sharp increase for sub-Saharan Africa, the region least able to sustain such a debt burden; the improving overall situation for Latin America and the Caribbean and Asia masks the serious difficulties faced by a small number of countries.
"On the 'open-minded' issue, yes, we will face serious difficulty so long as the issue of gay marriage remains on the table.
The authors conclude, "On the 'open-minded' issue, yes, we will face serious difficulty so long as the issue of gay marriage remains on the table".
"We understand and identify with the serious difficulties everyone is facing, but we can't let this misfortune be used as a premise to erode these bedrock principles".
Northern Ireland would face a "serious difficulty" if the United Kingdom votes to leaves the European Union, the Irish prime minister, Enda Kenny, has said.
This year Enda Kenny, Ireland's outgoing taoiseach, said Northern Ireland would face a "serious difficulty" if the UK voted to leave the EU.
The project of The Analysis of Matter does indeed face a serious difficulty with "Newman's problem", whether or not those difficulties arise for the earlier project of logical construction (see Linsky 2013).
"Our economy is faced with a serious difficulty, with prices rising and the economy gradually slowing," Mr. Lee said in a speech intended to observe the anniversary of the earlier pro-democracy protests.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com