Sentence examples for serious clinical problem from inspiring English sources

Equine endotoxemia is a serious clinical problem with high mortality.

Corneal alkali burns are a serious clinical problem that often leads to permanent visual impairment.

Successful restoration of large molar defects is a serious clinical problem.

Recently, persistent and chronic HEV infections have been recognized as a serious clinical problem, especially in immunocompromised individuals.

Stenosis of the left main bronchus caused by inflammatory diseases and neoplasms is a serious clinical problem because it can cause obstructive pneumonia and may require pneumonectomy.

Chylomicronemia in pregnancy is a rare, but serious clinical problem and can be found in patients with underlying molecular defects in the LPL gene.

It can cause serious clinical problems such as congenital toxoplasmosis, retinochoroiditis, and encephalitis.

To overcome serious clinical problems caused by large bone defects, various approaches to bone regeneration have been researched, including tissue engineering, biomaterials, stem cells and drug screening.

In the last few decades, the emergence of methicillin-resistant S. aureus (MRSA), vancomycin-intermediate S. aureus, vancomycin-resistant S. aureus, and community acquired methicillin-resistant S. aureus (CA-MRSA) has caused serious clinical problems [1], [2].

To gain further insight into the relation between the fudoh gene, colony spreading ability, and virulence, we examined colony spreading ability and the presence of the fudoh gene in CA-MRSA strains, which have high virulence and have been the recent cause of serious clinical problems.

Another most widely used metal-based drug at present against selected types of cancers is cisplatin [6], but use of cisplatin in curative therapy was associated with some serious clinical problems, such as severe normal tissue toxicity and resistance to the treatment [7].