Among the Elizabethkingia spp., the species Elizabethkingia meningoseptica is well established as a serious causative agent of neonatal meningitis and sepsis (Dooley et al. 1980), and a notable rise in E. meningoseptica nosocomial infections has been recorded in recent years.
Burkholderia mallei and B. pseudomallei, closely related Gram-negative bacteria, are causative agents of serious infectious diseases of humans and animals: glanders and melioidosis, respectively.
Their larvae are causative agents of serious diseases called echinococcoses.
Moreover, methicillin-resistant S. aureus (MRSA) have emerged as causative agents of serious infections in hospitals [ 15].
The problem of continuing increases in obesity and diabetes and their associated comorbidities and societal costs are sufficiently important to encourage serious endeavors to identify the causative agents.
Trypanosomatids, including Trypanosoma brucei, T. cruzi and different Leishmania species, are the causative agents of serious human as well as animal diseases, with a very high incidence and mortality rate if untreated.
The two basidiomycetous haploid yeasts, Cryptococcus neoformans and Cryptococcus gattii are causative agents of cryptococcosis, a serious disease that manifests as meningitis and meningoencephalitis in humans [5].
This type of pneumonia may represent a serious cause of illness and mortality among ICU patients [7], [8] However, the causative agents of pneumonia have not been completely identified [9].
Burkholderia mallei (Bm) and Burkholderia pseudomallei (Bp) are the causative agents of glanders and melioidosis, respectively, and are serious human health hazards mostly in Southeast Asia, Northern Australia, South and Central America, and the Middle East [ 1- 4].
Amphizoic amoebae generate a serious human health threat due to their pathogenic potential as facultative parasites, causative agents of vision-threatening Acanthamoeba keratitis (AK).
