Your English writing platform
Discover LudwigSuggestions(1)
Exact(6)
Serious bleeding during the infusion and 28-day period was similar between surgical and nonsurgical patients.
Serious bleeding during infusion: ENHANCE, 3.7%; PROWESS DrotAA, 2.4%; and PBO, 1.3%.
Serious bleeding during the treatment period occurred in 10 patients in the DrotAA group and 8 in the placebo group (P = 0.81).
The use of rFVIIa in serious bleeding during or after operations in the field of abdominal surgery has been described as effective and safe in various case reports and series.
In ADDRESS, recent surgery (within 30 days prior to study entry) was associated with a numerically higher risk of serious bleeding during infusion in both the Xigris-treated and the placebo-treated patients (Xigris: 3.6% in patients with recent surgery versus 1.6% in patients without recent surgery; placebo: 1.6% versus 0.9%, respectively).
Administration of DrotAA was associated with an increased risk for serious bleeding during the infusion period in both the overall PROWESS patients (P = 0.024) and the surgical cohort (P = 0.006); however, the surgical patients did not demonstrate excessive risk of bleeding compared with nonsurgical patients who received DrotAA.
Similar(54)
Anticoagulants are associated with serious medical errors, including major bleeding.
Among the preventable problems that Dr. Landrigan's team identified were severe bleeding during an operation, serious breathing trouble caused by a procedure that was performed incorrectly, a fall that dislocated a patient's hip and damaged a nerve, and vaginal cuts caused by a vacuum device used to help deliver a baby.
Fatal serious bleeding events during the infusion period occurred in 0.4% (12/2786) of cases.
Serious bleeding events during infusion of DrotAA were slightly more frequent in ENHANCE than in PROWESS; the proportion of fatal bleeding events was the same.
In ENHANCE, 6.5% of DrotAA-treated patients had serious bleeding events during days 0 to 28, and the incidence of CNS bleeds was 1.5%.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com