Sentence examples for serious alignment from inspiring English sources

The analysis of splicing by RNA-Seq has many caveats of statistical power, and there are still serious alignment errors that make accurate assessment of splice junctions problematic (Sturgill et al. 2013).

For these sequences, the default version of DIALIGN produces serious mis-alignments where entire genes are incorrectly aligned, but meaningful alignments can be obtained if the known gene boundaries are used as anchor points.

However, the many-to-one mapping problem becomes serious in network alignment.

It is well known that repeats cause serious problems for all alignment algorithms [ 12].

Stock option plans raise "immediate, and serious, issues of accountability and proper alignment of interests between management and employees on the one hand and shareholders on the other," Mr. Roiter said in May.

Level 3 data are global-grid data in the regular longitude latitude coordinate system, produced from the contents of Level 2. Non-negligible errors in navigational data and instrumental alignment can result in serious errors in the geometry calculations.

Altogether, we believe that the sequence alignments did not cause any serious errors.

Indeed, alignment-consensus methods may have serious limitations in describing polymorphic regions and may also cause biases in interpreting the effect of variation on coding sequences.

Some of them include: a serious deficiency of engineers; fragmented policies and poor alignment of national regulatory frameworks; cost of the technology and limited grid infrastructure.

When the sequence identity ranges from 25% to 50%, serious errors are prone to appear in the alignment.

The reported beam expanding units has the deficiencies of serious speckle effect of coherence and the strict tolerance of alignment, respectively.