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In the case of thrombin, these methods show that binding of the antagonist hirugen significantly alters the enzyme's correlation landscape through a series of pathways between Exosite I and the catalytic core.
Rather, it is now conceptualised as a series of pathways through childhood and a number of varied influences will determine which path a particular child takes.
A trade route is a logistical network identified as a series of pathways and stoppages used for the commercial transport of cargo.
Integration of the datasets shows that it is possible to link structure to pathology via the two layers of analysis allowing a reconstruction of a series of pathways.
At the late stage of infection, a series of pathways associated with inflammatory response and proliferation were identified (Table 2).
Furthermore, a series of pathways associated with inflammatory/immune response, cell proliferation, cell apoptosis, and developmental disorder were appraised.
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To further increase the FPP competitiveness of the lycopene synthesis pathway, we tried to enhance the catalytic performance of CrtE by directed evolution and created a series of pathway variants by varying the copy number of Crt genes.
To this end, we performed a series of pathway queries to amino acids from their respective precursors.
Moreover, Levine et al. reported interconnections between p53 and IGF1R/AKT/mTOR pathways where both LKB1 and MDM2 participate in a series of pathway cross-talks [ 67].
Regardless of the site of the mutation, these mutations result in loss of GTPase activity making this oncoprotein constitutively active and leading to activation of a series of downstream pathways including the RAF-MEK-ERK (MAPK) signaling pathway and AKT-PI3K-MTOR pathway (Fig. 1).
Its genome contains a complete set of genes related to the Wood Ljungdahl pathway, in addition to a series of metabolic pathways for acetic acid, butyric acid, and ethanol synthesis (Zhu et al. 2015).
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CEO of Professional Science Editing for Scientists @ prosciediting.com