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Data were also collected from the visit prior to the baseline visit (visit −1) and from two serial visits after the baseline visit (visits +1 and +2).
The Leicester cough questionnaire (LCQ) was done at baseline and during serial visits to evaluate cough intensity and was used as the primary outcome measure of the effect of CPAP therapy on chronic cough.
At serial visits throughout the study, the clinical status of the patient's intra-abdominal infection was assessed based upon the presence or absence of the following signs and symptoms: fever; localized or diffuse abdominal wall rigidity or involuntary guarding; abdominal tenderness or pain; ileus or hypoactive bowel sounds; nausea or vomiting.
The clinical status of the intra-abdominal infection was assessed at serial visits throughout the study by the presence or absence of the following signs and symptoms: fever; localized or diffuse abdominal wall rigidity or involuntary guarding; abdominal tenderness or pain; ileus or hypoactive bowel sounds; nausea or vomiting.
Eligible patients were evaluated, and clinical signs and symptoms recorded at serial visits: baseline (within 24 hours of first study drug dose), during treatment, early follow-up (Day 2-4 post-therapy), and test-of-cure (Day 10-21 post-therapy).
Assessment of immunosuppressant drug effects on serum IL-17 would be of interest; however, as we analysed patients followed for up to 10 serial visits, many changes in drug therapy occurred in individual cases, and together with variation in corticosteroid dose and disease activity the data do not allow us to make useful analyses of this question.
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Furthermore, the fee-for-service payment model incentivizes this passive, serial, visit-based care, such that traditional performance improvement strategies have limited effect on patients who are lost to follow-up or "fall through the cracks".
These models accounted for the correlation between serial measurements at consecutive visits from each person and were implemented using the Proc routine in SAS.
To address the correlation of multiple events occurring close together in time (e.g., an ER visit leading to an admission, or serial ER visits), the occurrence of events were classified as "one or more events" or "no events" in each of the "at-risk" and control periods.
Often times serial office visits are required to clinch the diagnosis, and frequently these symptoms will resolve before a diagnosis is made.
This is followed by serial antenatal visits with a midwife which include measurement of the symphysis-fundal height with a tape measure, measurement of blood pressure with a sphygmomanometer, and urinalysis.
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