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Here, a panel of experts judge how well the Serial treatment will fit this most contentious of cases.
Late in 1907 Braque embarked on a serial treatment of a little place called L'Estaque in the south of France (its houses, trees, roads, viaduct), which evolved over the next few months into a style of painting that had no name, no school, no code and no precedent - painting that left his peers breathless and his critics stunned.
Serial treatment of the suspension cultures with noggin and granulocyte colony-stimulating factor significantly increased the number of cardiomyocytes by more than fourfold compared with untreated cultures.
Serial treatment of MJ, SA and YE at 24 h intervals enhanced the accumulation of dihydrosanguinarine (2.5 times) and sanguinarine (5.5 times).
Use of endoscopic submucosal dissection (ESD) for management of widespread superficial esophageal carcinomas may be complicated by the development of severe strictures, which may require serial treatment with endoscopic balloon dilatation (EBD).
Nafion membrane was exposed to serial treatment to remove contaminations which include washing the film for 1.0 h, immersion in 3.0% H2O2, following washing with double-distilled water, re-immersing in acidic solution and eventually re-exposing to distilled water, respectively.
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Or alternatively, new feedback loops may be inserted into the signaling system to induce relevant counter-acting states (e.g., disruption of signal relays and cell dormancy) or to improve its sensitivity to serial treatments.
Consistent with the observation that pre-GEPCOT cells were sensitive to serial TMZ treatment, we detected little recovery of dividing SVZ cells, NICs, or GEPCOTs after serial TMZ treatment.
Nonetheless, this study paves the way for quantitative analysis of drug responses at the promoter level, and moreover, it is potentially applicable for the evaluation of combinatorial or serial drug treatment in a clinical setting.
Finally, in the multi-dose phase of the study, pre-treatment tumor biopsies were collected (as described above for dose-escalation) and serial post-treatment tissue samples acquired on days 7, 28 and 56 of treatment if applicable.
Serial on-treatment ECGs were available from 27 patients.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com