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Signaling pathways consist in the serial activation of several molecules, mainly proteins, by chemical reactions that change their conformation.
While roles for the PI-3K and PP2B pathways were dismissed, we demonstrated serial activation of ERK and RSK upon NMDAR activation.
The enhanced speed is due to more efficient serial activation of a downstream signaling module (by the signaling molecule immediately upstream in the cascade) at points distal from the signaling origin, compared to locations closer to the source.
These TDNs provide hypotheses for mechanisms underlying serial activation of key DRPs and their temporal associations.
Serial activation of the tyrosine kinases LCK and ZAP-70 initiates signaling downstream of the T-cell receptor.
However, the DNs delineate no temporal transition of the DRNs and/or their edges to represent serial activation of cellular processes over time.
Similar(48)
Ordered serial activations of specific neural subsets were also observed with single units in vivo in S1 cortex of rats [10].
Until recently it would have been difficult to envision mechanisms of serial transcriptional activation in the Apicomplexa.
Multiple extracellular stimuli can initiate a cascade of serial phosphorylation activation from MAP kinase kinase kinase (MAPKKK) to MAP kinase kinase (MAPKK) and finally MAPK.
The present study examined the expression of serial platelet activation markers (CD62P and CD63) and the three-month outcome after acute non-cardio-embolic ischemic stroke and produced four major findings.
To the amazement of many Windows refugees, Mac OS X requires no serial number and no "activation"; it's not copy-protected.
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