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These results suggest that the separation of the checkpoint into two branches also reflect a functional division: The Mad2-branch promotes Mad2 activation and consequently Cdc20 sequestration, whereas the Bub3/Mad3 branch induces the formation of the Bub3-Mad3 complex which promotes Cdc20 degradation.
Also this RNA retained its sensitivity to miR-122 sequestration, whereas the overall translation efficiency was reduced.
L-selectin-deficient mice exhibit attenuation of prolonged (5 min after complement injection) capillary sequestration, whereas rapid PMN accumulation is only reduced in noncapillary vessels [ 17].
Additional inhibition of E-selectin and L-selectin further attenuated PMN sequestration, whereas inhibition of these selectins alone had no effect [ 21].
At the global scale, wilderness coincides with areas important for carbon storage and sequestration, whereas hotspots better support water provision and the grassland production of livestock (Naidoo et al. 2008).
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These two motifs cause a substrate to act as a coupled system in which a unidirectional cycle generates single-molecule oscillators, whereas sequestration synchronizes the population by limiting the available enzyme under conditions in which substrate is in excess.
Whereas sequestration in the peripheral microvasculature is associated with IE that bind CD36 and variably to other host receptors, chondroitin sulfate A (CSA) expressed by placental syncytiotrophoblasts has been described as a common receptor involved in IE placental sequestration [3].
For chemical contaminants, biodegradation, transformation, and volatilization are expected to increase (Table 3), whereas sequestration of sorptive contaminants might decrease because soil organic carbon is predicted to decrease (Falloon et al. 2006; Smith et al. 2005).
The unphosphorylated form of MARCKS binds to actin filaments, leading to cross linking and sequestration of membrane phospholipids, whereas phosphorylation by PKC abrogates membrane binding of MARCKS.
It has been suggested that phosphorylation of tau at S199, S202, T205, T212, S235, S262 and S404 is required for the sequestration of normal tau, whereas further phosphorylation at positions T231 and S396 is needed for self-assembly.
Failing metal homeostasis in DRG neurons may contribute to endogenous Zn toxicity whereas Fe sequestration in holoferritin of hyperplastic satellite cells may be neuroprotective.
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