From animal and human post mortem studies accumulation of many dioxin-like compounds to liver is known to take place by dose-dependent induction of CYP1A2 protein capable of hepatic sequestration of these compounds.
Sequestration of these compounds in acidic lysosomes is visible after incubation in most cases, and no fluorescence was observed in the nucleus.
This transit of blood through the extracorporeal circuit may result in degradation and/or sequestration of circulating compounds, including administered drugs [ 5].
The sequestration of these compounds, which often show antimicrobial activity [ 64, 66], might provide a certain kind of resistance to microbial attacks.
The multidrug resistance-related protein (MRP -type ABC transporters have been iMRP -type in the vABColar sequestransportershavelic compounds such as flavonoids and anthocyanins, and flavonoids have been suggested as negatimplicatedtors of MDR-type members (for revinw: [ 84]).
Unless direct evidence demonstrates the detoxification or sequestration of insecticide compounds by P450s, the conclusion that the 7 up-regulated P450 genes are involved in OP resistance is too early to draw.
Various classes of multi-drug resistance, MATE efflux and other types of proteins involved in the extrusion or sub-cellular sequestration of toxic compounds were in this group [ 96, 97].
The lipocalins are a widespread family of proteins that naturally serve in many organisms, including humans, for the transport, storage, or sequestration of small biological compounds like vitamins and hormones.
The addition of select polymer beads to stirred tank bioscrubber systems has been shown to greatly enhance the removal and treatment of toxic VOCs via the capture and sequestration of poorly soluble compounds such as benzene, and the release of these materials, based on equilibrium partitioning, to microorganisms in the aqueous phase.
Proposed internal tolerance mechanisms include chelation of Al by organic acid anions or phenolic compounds and sequestration of Al in the vacuole [ 5].
The mechanisms like extracellular (chelation and cell wall binding) and intra-cellular (binding to compounds like proteins) sequestration of heavy metals have been proposed as mechanisms for heavy metals tolerance in fungi (Fawzy et al. 2017).
