Sentence examples for sequestration of cells from inspiring English sources

Figure 6A shows that 72 hours after injection, small numbers of transferred EGFP+ cells continued to circulate despite significant sequestration of cells in the lymphoid tissues of EAU mice treated with CD62L or CD44 mAbs.

An alternative approach is to control the cellular microenvironment through biomaterial-mediated sequestration of cell-secreted proteins important to differentiation.

To determine if observed changes were due to sequestration of cell-secreted protein, the proteins sequestered by heparin microparticles were analyzed using SDS-PAGE and mass spectrometry.

These results indicate that heparin microparticles modulated chondrocytic differentiation in this system via sequestration of cell-secreted protein, a technique that could be beneficial in the future as a means to control cellular differentiation processes.

They investigated two mechanisms for MSAC in metazoan cells: one involves free diffusion and sequestration of cell cycle regulators requiring a two-stage signal amplification cascade.

Sequestration of cell cycle inhibitors (p21 and p27) is well established for D-cyclins [ 3].

Since the formation of autophagosomes is normal in pep4 mutant yeasts (and presumably the sequestration of cell cycle regulators within the vacuole should be unimpaired), the mitotic arrest phenotype observed in our study is unlikely due to a specific requirement for autophagy-dependent proteolysis of a cell regulator(s) during nitrogen starvation conditions.

The authors hypothesized that particles enter lung endothelial cells or erythrocytes and subsequently influence red cell adhesiveness, leading to peripheral sequestration of red cells.

Increased numbers of antigen-specific T cells in vivo after silencing of Prnp allow several explanations: (i) a decreased sequestration of these cells from secondary lymphoid organs into other compartments; (ii) a decrease of Fas-mediated apoptotic cell death; (iii) a diminished growth factor withdrawal due to decreased antigen-specific proliferation or (iv) a push of these cells into cell cycle.

In vivo treatment with fingolimod (FTY720), a drug that causes sequestration of T cells in lymph nodes [18], was used to further characterize T-cell redistribution to Ag-free lymph nodes.

Impaired T cell-mediated immunity in such patients could be due to the sequestration of T cells within organs affected by sarcoid, such as the lung.