Exact(4)
The highest affinity peptides showed a reduction in bioactivity consistent with their sequestration away from their protein target in the presence of 0.1% rabbit serum albumin.
Such tissue tolerance can be achieved by efficient Na+ sequestration away from the cytosol (where it can affect the metabolic processes of the cell) into the vacuole.
Conversely, this sequestration away from the cytoplasm, as well as inducible export of cytoplasmic zinc from macrophages, may also enable these cells to starve certain pathogens of zinc to limit growth.
Although it is consistent with Nika et al.'s results, it is possible that there remains a pool of Lck that cannot be activated acutely by Csk inhibition, due to sequestration away from Csk, proximity to CD45 or another mechanism.
Similar(4)
Sequestration cannot do away with the right to counsel for indigent defendants, so the hundred or more defendants who ordinarily would be represented by a federal defender in new cases between now and September will likely end up with court-appointed private lawyers.
Sequestration, not going away anytime soon, means that current troop levels will be fiscally impossible to sustain.
The budget trims heating assistance to $3.02 billion, a reduction of $346 million from what was left after "sequestration" cuts took away $175 million starting in March.
The production of E1A mRNA within hepatocytes that contains multiple microRNA binding sites could lead to the sequestration of mir122 away from its endogenous mRNA targets or depletion of the total mir122 content in the cell.
Related(2)
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