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In this study, patients were engaged in a task of somatosensory discrimination that required repeated encoding, maintenance and retrieval of information for comparison of sequentially explored objects over an extended period of time (see methods section below) and thus demanded a high degree of attention and working memory.
In a recent study exploring somatosensory discrimination by fMRI we were able to show that the right prefrontal cortex is involved during the phase when retrieval of information from episodic memory is critical for the comparison of sequentially explored objects [ 44].
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When more than one significant covariate for the simple model was found, the covariate-adjusted model with the largest decrease in objection function was chosen as a basis to sequentially explore the influence of additional covariates using the same criteria.
Then, sequentially adjusted models explored the effect of adjustment for traditional CVD risk factors: DBP (Model 2), lipid (LDL-c, HDL-c, TG: Model 3), BMI (Model 4), microalbuminuria (Model 5), smoking status (Model 6), the combined model with all CVD risk factors (Model 7), and a final model with all covariates and HbA1c (Model 8).
Sequentially, to further explore the molecular mechanisms by which miR-224 exerts its function, the determination of its functional target gene is essential.
Sequentially, cognitive radio techniques are explored, and an adaptive channel switching mechanism is proposed to mitigate channel interferences in the crowded ISM band.
Moreover, the possibility of providing a predictive modelling platform for residual strength prediction of environmentally aged joints using sequentially coupled moisture diffusion-fracture analysis is explored.
Predictors were explored one at a time, sequentially.
Associations were explored with logistic regression modelling controlling sequentially for potentially confounding factors; age, gender, ethnicity and lone parenthood.
The tree space was explored using Markov Chain Monte Carlo (MCMC) analyses with random starting trees, five simultaneous, sequentially heated independent chains sampled every 500 trees during five million generations.
To test this hypothesis, we sequentially determined the development of implant osteomyelitis by F-FDG microPET scanning of contaminated and uncontaminated rabbit tibiae and explored its possible use in diagnosis of implant infection.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com