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For ethical reasons, these studies are usually sequential, treating patients or groups of patients with the optimal dose according to the current knowledge, with the hope that this will lead to using the true MTD from some time on.
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6, 23, 26, 27 Sequential analyses treat current behaviors as probabilistically determined by recent and adjacent behaviors.
Four hundred and thirty nine sequential patients treated with neoadjuvant treatment for operable breast cancer at the Royal Marsden Hospital between 1985 and February 2003 were considered for this analysis.
This project is designed to directly examine these provider concerns by evaluating the benefits and harms of an integrated versus a sequential approach to treating comorbid PTSD and SUD.
No consensus exists for the appropriate sequential approach in treating LPHS.
In the sequential approach to treating comorbid anxiety and AUDs one disorder is treated prior to addressing the other disorder.
But Elling generally does his work without altering melody but by treating the sequential measures of a song unconventionally.
Furthermore, we have discussed the duration of treatment; sequential vs combination treatment; treating elderly and poor performance status patients; oral fluoropyrimidines as well as management of resectable metastasis.
In the previous experiments, combination treatments were performed in a sequential format by first treating cells with a sensitizing drug for 24 hours, removing the drug from the cells, and then applying a TRAIL treatment for an additional 24 hours.
Prospective efficacy data have recently been presented from a phase III sequential study to treat RCC (SWITCH) (Michel et al, 2014); this study directly compared sunitinib sorafenib vs sorafenib sunitinib sequential therapeutic approaches (NCT00732914).
To ensure physical limits we treat sequential work-driven operations, in particular those of dissolving or evaporation which run jointly with thermal machines (e.g. heat pumps).
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