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A significant linear relationship between flow and concentration and sequential time points was not common at the decentralized sites.
In longitudinal studies, three-dimensional (3D) bone images are acquired at sequential time points essentially resulting in four-dimensional (4D) data for an individual.
Peripheral blood was obtained from pediatric liver transplant patients at sequential time points: pre-transplant, one month, 3-4 months, 6-7 months, and 11-12 months post-transplant.
Various hemodynamic parameters were measured using direct pressure signals and continuous arterial waveform analysis at three sequential time points: before, during and after hyperoxia.
All measurements were performed with patients in supine position at three sequential time points: pre-intervention, during intervention and post-intervention.
Symptoms were assessed at sequential time points by the Structured Interview for PTSD (SIP), a clinician interview based assessment, and a self-report scale, the Davidson Trauma Scale (DTS).
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We have used a similar approach combining a sequential time point study with extensive histopathological and immunohistochemical analysis of selected tissues to study the pathogenesis of BSE in sheep.
This non-invasive in vivo imaging provides a means by which to follow the course of inflammation in real time and may allow investigators to study animals longitudinally without the need to kill them, thus reducing the number of animals required for sequential time point analyses.
We used treatment as a fixed effect and introduced an error term for the two sequential time-points when each population was sampled.
Analysis of the HCV non-structural protein NS2-NS5B sequences from sequential time-points of subjects with acute and early HCV infection revealed a total of 170 amino acid changes, the majority of which were maintained into chronic infection (108/143 mutations in subjects with multiple time-points; Table S1).
Outcome assessment was based on quantitative CRP concentrations measured at sequential time-points after surgery.> The degree of operative trauma was arbitrarily categorized into three types of surgery.
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