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And sequential tests are suboptimal because you're not measuring what happens when factors interact.
Group sequential tests are widely used for interim analyses in randomized clinical trials.
Sequential tests are ideal for multi-day outbreaks so the performance (the false negative rate for a fixed false positive rate) of Page's statistic or a moving window such as in [ 28] or the scan statistic such as in [ 29] would be better than the performance of one-at-a-time tests in the case where all simulated outbreaks lasted 7 days.
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In hopes of improving its predictive value, some doctors suggest that when the reading is minimally elevated, sequential tests be done a year or more apart, with a biopsy performed only when the P.S.A. rises by 25percentt or more.
Due to the optional sampling effect in a sequential design, the maximum likelihood estimator (MLE) following sequential tests is generally biased.
Also, sequential tests were not used in [ 27] for their 7-day simulated outbreaks.
Sequential tests were conducted on a Linux machine equipped with an Intel P4 3 GHz processor and 2 Gbytes of memory.
The primary analysis (sequential test) was performed using the SAS software (SAS® software, version 9.2, for Windows (SAS Institute, Cary, NC, USA)).
Sequential testing is another type of hypothesis testing, which requires a variable number of samples to make decisions.
When there are more than one Activity Area, the sequential testing is applied to each Activity Area separately, since there could be more than one different activity taking place.
Such sequential testing is typically more cost-efficient than parallel testing, because previous knowledge often allows one to design experiments in a more informative way.
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