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Note that the advantage of the W-curve over the CGR is that local sequential base positions are projected onto the Z axis from the X-Y chaos game plane.
Eg, a higher-order dinucleotide sequence model is able to account for the dependency between two sequential base pairs.
For the modified strand, the anticipated pattern of sequential base aromatic→deoxyribose anomeric nuclear Overhauser enhancement (NOE) was identified from C→T.
Nucleic acid hybridization, the sequential base pairing between complementary probe and target strands, results in the formation of stable double-stranded duplexes.
Due to the limitations of short read sequence alignment, the analysis between N2 and CB4858 is limited to sequential base substitutions, indels, and putative inversions with a length of 2 bp.
Following the hybridization of the 5'-anchor region of a guide RNA (gRNA) to the 3' end of its target message, sequential base pairing directs U insertion and deletion in a processive enzyme cascade [ 6].
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Currently, the number of sequential bases that SBL-based approaches can sequence is limited by loss of specificity of base pair hybridization at any distance away from the site of ligation.
Residue number 13 in each TAL repeat (one of two consecutive polymorphic amino acids that are termed 'repeat variable diresidues', or 'RVDs') specifies the identity of a single base; collectively the sequential repeats and their RVDs dictate the recognition of sequential bases along one of the two DNA strands.
The 250-bp reads were truncated at any site of ≥3 sequential bases receiving a quality score < Q10, and any read with <75% (of total read length) consecutive high-quality base calls was discarded (Bokulich et al., 2013c).
Model fitting was sequential based on the most significantly associated individual variable, with model fit assessed using the Akaike Information Criteria to ensure fitting the most parsimonious model given the small number of outcomes available for evaluation.
The collection of these data predated revisions to the definition of CKD that now incorporate both eGFR and UACR simultaneously; during the time of this study testing was sequential (based on local guidelines) and eGFR-UACR "paired" samples uncommon.
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