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Absence of LRP1 expression results in increased PDGFRβ signaling and sequential activation of the mitogen-activated protein kinase signaling pathway, which increases phosphorylation of cytosolic phospholipase A2 (cPLA2).
On the other side, 1,25-dihydroxyvitamin D3 is known to stimulate DNA synthesis via sequential activation of Raf and the mitogen-activated protein kinase [29].
These specific conformational states involve the sequential activation of the Ffh and FtsY active sites after binding of GTP and during the formation of the targeting complex.
Sequential activation of neurons is a common feature of network activity during a variety of behaviors, including working memory and decision making.
Ubiquitination occurs via sequential activation and conjugation of ubiquitin to target proteins by ubiquitin activating enzyme (E1), ubiquitin-conjugating enzyme (E2) and ubiquitin ligase (E3) [1].
(B ) Various states of activity for Hoxd genes in different samples, analyzed during sequential activation.
Indeed, as observed in other tissues, the cardiac specific transcriptome dynamics revealed the sequential activation of ecdysone responsive genes, which are known downstream effectors of activated EcRs.
The eukaryotic cell cycle is tightly regulated by the sequential activation and deactivation of the cyclin-dependent kinases (CDKs).
We use this process of sequential activation as our definition of an avalanche and our main interest is the distribution of the avalanche sizes.
The sequential activation of the hepatocyte nuclear factors (HNFs) like HNF1β and HNF6 expressing in endoderm and Pdx1 modulate the generation of pancreatic progenitors[44].
The improved mechanical properties are attributed to the high yield strength of the recrystallized grains and the sequential activation of dislocation slip and dislocation channeling.
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