Sentence examples for sequencing of populations from inspiring English sources

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Even whole-genome sequencing of populations, the ultimate genome diversity survey tool, reveals at most the potential of a population to express various phenotypic features.

A recent study has quantified the temporal dynamics of point mutations over 1000 generations by deep sequencing of populations (Lang et al. 2013).

Further studies, such as single-cell RNA sequencing of populations of interest, are warranted to further characterize the heterogeneity of these populations.

Sequencing of populations at different evolutionary times shows that the number and type of mutations are compatible with other laboratory evolution experiments, which are characterized by competition between variant clones (Barrick et al. 2009; Bachmann et al. 2012).

With increases in the throughput of sequencing technologies, the approaches applied for genetic variation analysis start shifting from the usage of SNP-based genotyping assays to the direct sequencing of populations (Hamilton and Buell 2012).

Resequencing from original stock material, as well as consensus sequencing of populations that had been serially passaged three times in Vero cell culture, confirmed that the passaged strain was 100% identical to the parental population and that the sequence shared one of the signature amino acid substitutions characteristic of the San Martin/Huanuco clade.

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The ability to easily develop custom panels of SNP markers for interrogating genes or genome regions of interest will complement modern genetic strategies that identify candidate variants through deep sequencing of population samples.

Now let's consider a sequence of populations with probability distributions P N ={p 1,p 2,…,p N−1,P N,+}, where (p_{N,+}=sum limits _{i=N}^{infty } p_{i}).

This was done only for the leopard cat since sequences of populations from outside India were available only for this species [23].

Previous phylogeographic analyses of mitochondrial cytochrome oxidase I (COI) sequences of populations of C. ebraeus in the Indo-West Pacific show no evidence of population genetic structure among samples from these regions [18], a pattern that is not necessarily unexpected given the potential for wide dispersal in this species due to a three to four week planktonic larval stage [19].

Until high-throughput sequencing becomes more affordable and bioinformatical advances allow routine whole-genome re-sequencing of populations, we expect that reduced-genome-complexity approaches will remain essential for population genomic studies particularly in non-model organisms with large genomes.

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