Sentence examples for sequencing focus from inspiring English sources

Upon completion of model organism genomes like Saccharomyces cerevisiae, Caenorhabditis elegans and others, comparative sequencing has gradually moved into the sequencing focus.

Traditional methods using Sanger sequencing focus on small groups of genes and therefore are unable to screen for numerous genes from several patients simultaneously.

This question is being addressed in the current UK Medical Research Council phase III trial 'Fluorouracil, Oxaliplatin and CPT-11: Use and Sequencing' (FOCUS), which uses the MdG, OxMdG and IrMdG regimens as described here.

Exome sequencing focuses specifically on generating reads from known coding regions.

A follow up study, summarizing information from whole Y chromosome sequencing, focused specifically on this Ashkenazi Levite lineage and confirmed that that 65% of the 97 randomly assembled Ashkenazi Levites carried haplogroup R1a-M19820.

For example, BWASW, SHRiMP2, SMALT, SSAHA2 and TMAP, might perform particularly well for sequencing focused on rare variant discovery because they show a robust discrimination of variations.

The sample found negative by a-CGH was further analysed by conventional Sanger sequencing focusing on the same exon recognised as deleted by MLPA.

We mainly attribute these differences to a more sensitive mutation calling by conventional Sanger sequencing focusing on previously determined genomic hotspots compared to the explorative whole exome next-generation sequencing approaches [ 9, 10] using rather low read depth.

Transcriptome sequencing focuses on deciphering the complex expression pattern of RNAs [ 2, 3], therefore identifying novel expressed RNAs and transcript variants as well as isoforms which in turn lead to a better understanding of cell regulation, function and networks.

Usually genome searches that aim to find variation in coding sequences focus on translations since non-synonym amino acid variation is generally believed to produce phenotypic variation.

One sequence focuses on a cluster of beluga whales turning frantic somersaults, their thin bodies scarred by assaults from bears.