Hennekam, R. & Biesecker, L. G. Next-generation sequencing demands next-generation phenotyping.
A control object discrimination task was designed to be comparable to the sequencing task regarding semantic, visuospatial, and motor processing requirements but without sequencing demands.
We present a method of targeted ancient DNA sequence retrieval that greatly reduces sample destruction and sequencing demands and use this method to reconstruct the complete mitochondrial DNA (mtDNA) genomes of five Neandertals from across their geographic range.
However, the genome-scale metabolic networks now being reconstructed from annotation of genome sequences demand new network-based definitions of pathways to facilitate analysis of their capabilities and functions, such as metabolic versatility and robustness, and optimal growth rates.
Its chilly widescreen vistas and adrenalin-pumping action sequences demand to be seen on the big screen.
If Webb took care of business there — which he has — they could always surround him with canny Oscar-nominated veterans like cinematographer John Schwartzman and visual effects supervisor Jerome Chen — as well as four members of the stunt coordinating Armstrong family — to take care of the heavy lifting the major action sequences demand.
GC-rich sequences demand higher melting temperatures to be converted into and kept as single stranded DNA molecules.
Characterization of an increasing number of broadly neutralizing antibodies specific for pathogen surface proteins, the growing number of known 3D structures of antigen-neutralizing antibody complexes, and the rapid growth of the number of viral variant sequences demand systematic bioinformatics analyses of B-cell epitopes and cross-reactivity of neutralizing antibodies.
As more of the human genome draft sequence is finished, and genomes from other organisms begin to be sequenced, the demand for accurate and reliable genome annotation will increase significantly.
With new sequencing technologies allowing many more eukaryotic genomes to be sequenced, the demand for collaborative annotation is likely to increase.
I used to be a purist about action sequences, demanding that bodies in combat be seen in full frame and without too much cutting.
