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Limited sequencing analysis of mutant clones from 0.25 or 1 Gy exposures revealed a higher frequency of deletions and multiple base sequencing changes with increasing dose.
In addition, with the advent of personalised medicine, there is a compelling need for rapid and accurate methods for detection of nucleic acid sequencing changes, such as, KRAS mutations, in clinical specimen (Krypuy et al, 2006).
To validate the sequencing changes in the genes of interest, we used intragenic revertants for NG6 (Huang et al. 1981; Miller et al. 2005) and transformation rescue for NG30 (Iomini et al. 2009a).
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Each sequence changes the distribution chain".
small sequence changes (SNVs, indels, block substitutions).
Viral sequence changes in the SBBC will be considered.
Some property differences of the isomers caused by the sequence changes were found.
Do these features relate to robustness — the ability to readily accumulate sequence changes?
We classified SNVs, small indels and block substitutions as small sequence changes (SSCs).
Dark blue arrows indicate the sequence changes in one of the TRIM lines.
Some of the sequence changes were then validated by the dye-terminator method.
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