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We report on the development and characterization of 106 EST markers from chickpea sequences with functional annotations or unknown functions, some of which contain SSR motifs.
We investigated the effects of combining different classifiers to better annotate protein sequences with functional terms defined in the molecular function aspect of GO.
The recent study by Thurman et al. [ 16] made it possible for the first time to analyze the regulatory regions by querying their sequences with functional elements with known (or suspected) pathogenic functionality.
Following previous studies, future endeavor in this field is suggested to focus on designing more peptide sequences with functional motifs not only to summarize general rules to predict self-assembly but also to realize practical applications.
In this study, we try to integrate primary sequences with functional features, including KEGG pathways, GO terms, protein-protein interactions and protein functional domains, to predict phosphorylation sites.
When the human genome became available, identification of all its functional genomic elements still remained difficult, and genomic comparisons have frequently been used to identify sequences with functional potential.
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Mp-MRI consists of T2-weighted sequences combined with functional sequences including dynamic contrast-enhanced MRI, diffusion-weighted MRI, and magnetic resonance spectroscopy imaging.
During her PhD, she worked in collaboration with Broad Institute of MIT and Harvard to bridge the high-throughput data result of human genome sequencing with functional and translational studies related to type 2 diabetes.
By coupling 16S ribosmal RNA sequencing with functional magentic resonance imaging in patients with major depressive disorder, a disease associated with an altered GABA-mediated response, we found that the relative abundance levels of faecal Bacteroides are negatively correlated with brain signatures associated with depression.
Therefore, in this study, we used a proton density-weighted HASTE sequence, with functional contrast based on signal enhancement by extravascular water protons (SEEP), and a motion-compensating GLM analysis to (i) characterize the SEEP response function in the human cervical spinal cord and (ii) demonstrate the feasibility of event-related spinal fMRI.
A useful indicator to identify a sequence with functional relevance is conservation through evolution.
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