Sentence examples for sequences with altered from inspiring English sources

We sought to test this mechanism of primer termination by design of DNA primer sequences with altered conformational properties.

Whereas existing gene drive proposals focus on adding genes (Ito et al., 2002), disrupting existing genes (Burt, 2003), or suppressing populations, RNA-guided gene drives will also be capable of replacing existing sequences with altered versions that have been recoded to remove the sites targeted by the drive.

New exon combinations can be generated by recombination within the intervening intron sequences, yielding new rearranged genes with altered functions.

These edited mature miRNAs with altered "seed" sequence are likely to suppress a set of genes different from those targeted by unedited miRNAs.

Randomized sequences are then cloned into a suitable expression vector, and the resulting mutant libraries can be screened to identify mutants with altered or improved properties.

With altered destinations".

A total of 723 coding sequences were significantly altered, with 287 upregulated and 436 downregulated; the microarray-observed expression was validated by quantitative PCR on five selected genes.

Such exons may have originated from old repeated sequences, with splicing sites altered by mutation, and gained functions with time, and eventually became more frequently spliced.

Our findings have revealed for the first time that certain factors may have critical influence on the splicing frequency, suggesting that exons with lower splicing frequencies may originate from old repetitive sequences, with splicing sites altered by mutation, gaining novel functions and become more frequently spliced.

The selected sequences were altered by introducing glycine linkers with terminal cysteines at both amino and carboxyl terminus of the peptide designs.

PCR products with alter chromatograms were sequenced using ABI 310 sequencer.