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We excluded sequences whose position within a tree was sharply in conflict with the uncontested animal phylogeny.
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Sequences whose positions did not meet the following checks were discarded: 1.Chromosome and strand of the TSS position and of the best BLAT hit match.
FastBLAST clusters together sequences whose aligned positions are over 33% identical (see Methods for details).
* Data including sequences whose exact positions were not determined.
For these reasons, according to siRNA design guidelines and the CYP3A4 gene sequence, we chose three novel sites targeting the coding regions whose position in gene sequence were 773 794, 923 944 and 1191 1212, respectively.
A computer generated virtual partner (an avatar of a hand) is constructed using an animated sequence of index finger movements whose position is selected based on a mapping from the variable x.
The pattern results from a nucleosome whose position depends on sequences within the UASG.
In the rare families where there were two sequences from the same species, the sequence showing the largest terminal branch length or whose position was most at odds with the NCBI classification was discarded.
In contrast, if a signature was extracted from mRNA sequences whose transcriptional orientation, polyadenylation features, or position information was unknown, or had been found only in non-coding regions or repeated structures, it was filtered out.
Paralogous sequences whose mature miRNAs differ at only one or two positions are given lettered suffixes: for example, miR-10a and miR-10b.
Paralogous sequences whose mature miRNAs differ at only one or two positions are given lettered suffixes, for example, mmu-miR-10a and mmu-miR-10b in mouse [ 41].
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