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All these sequences were picked by p53retriever as potentially functional.

The occurrences of each selected motif in the input set of sequences were picked using the 'locator' program.

A total of 454 raw reads that yielded BLAST hits against the seed sequences were picked up and assembled using Newbler (version 2.6).

Because of their similarity to PTPs, human Styx sequences were picked up in our HMM search and are highlighted on the tree in Fig. 5.

In addition to 151854 sequences commonly detected across all genomes, 24878 sequences were picked up using FPfam that were missed by Pfam, while only 3603 found with Pfam were missed by FPfam (for further details, see section on domain instances missed by Pfam below).

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Six sequences are picked from this population by selecting the best model-fitting one and five (if available) more with progressively increasing of the E-value.

Operational taxonomic units (OTUs) were picked by using de novo OTUs picking protocol with a 97%% identity threshold, then a representative sequence was picked for each OTU and using the RDP (http://rdp.cme.msu.edu) classifier (Wang et al. 2007) to annotate taxonomic information for each representative sequence.

A rhesus exon sequence was picked as target only if it matched the exon regions of the 23,000 human genes (Human UniGene build 167).

Each base position in that random sequence was picked from all 4 bases having equal probability (0.25) of being selected.

Transformant E. coli clone (1 discrete colony), confirmed by PCR and sequencing, was picked into 200 mL of 2x YT broth in a 2 Litre flask and shaker-incubated at 35°C for 5 hours to mid-log phase (OD600nM = 0.7).

Possible PCR-mediated recombination errors as well as homopolymer run-associated sequencing errors were picked up manually by checking the pairwise alignments resulting from the FASTA search.

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