Sentence examples for sequences to mediate from inspiring English sources
These biomolecular scaffolds exploit the properties of natural protein sequences to mediate targeted cellular events [9].
In contrast to the AT-1s discussed above, the TPS system consists of two separate proteins; an outer membrane β-barrel protein (TpsB) and a cognate substrate protein (TpsA) both containing signal sequences to mediate inner membrane translocation.
A TF contains one or more DNA-binding domains (DBDs), which bind specific DNA sequences to mediate the binding of RNA polymerase at the onset of transcription initiation.
Some uORFs, however, do rely on peptide sequences to mediate translational regulation of the associated mORF, but few examples have been identified and characterized to date.
In 2006 Peterson proposed the N-terminal extension of the signal sequences to mediate an interaction with an unknown cytosolic factor or to induce an unusual signal peptide conformation prior to protein translocation.
The MERES motif found within p22 is somewhat unconventional for an ER export signal in that p22 does not encode a signal sequence to mediate ER import, is not glycosylated, and is not exclusively ER localized at any point during expression (Figure 4D and data not shown).
A recent study has identified a plant specific DNA binding protein, PEAPOD2 (PPD2), that specifically binds to sequences known to mediate activation of the CP promoter of CaLCuV and TGMV in mesophyll cells [ 17].
The binding pattern between HSP72 and 1 mM MV-N peptide was similar to that of HSP72 and 1mM peptidetide, a positive control based upon sequences known to mediate p53-HSP72 interaction (20).
Transcriptional regulation by AC2 appears to be mediated through interaction with a plant specific DNA binding protein, PEAPOD2 (PPD2), that specifically binds to sequences known to mediate activation of the CP promoter of Cabbage leaf curl virus (CaLCuV) and Tomato golden mosaic virus (TGMV).
We have recently shown that the CaLCuV CP promoter is regulated by AC2 through an interaction with PPD2, a plant specific DNA binding protein, that specifically binds sequences known to mediate activation of the CP promoter of CaLCuV and TGMV [ 17].
The presence of a Glu-Lys-Gly triplet in the middle of the sequence appears to mediate this staggered molecular packing through its indirect water-mediated interactions with backbone CO groups and side-chains.
