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Interestingly, convergent genes, in which two RNA polymerases could potentially collide, do not usually exhibit transcriptional interference [ 2, 3], due to the presence of sequences that act as transcriptional terminators, acting on both strands [ 4].
A single long strand of DNA is studded with shorter snippets of specially designed DNA sequences that act as the chemical equivalent of staples.
Central to the cell type-specific transcriptional regulation are distal cis-regulatory elements called enhancers, canonically defined as short noncoding DNA sequences that act to drive transcription independent of their relative distance, location or orientation to their cognate promoter.
Meanwhile, to identify DNA sequences that act as transcriptional enhancers in a direct, quantitative, and genome-wide manner, the STARR-seq has been developed by taking advantage of the knowledge that enhancers can work independent of their relative locations19,20,21.
First a bit of background: Telomeres are special DNA sequences that act as "caps" on both ends of every chromosome, providing a kind of protection for your genes.
Essentially, one of the keys to immortality lies in telomeres — which are essentially a region of nucleotide sequences that act as a protective cap, deterring the degradation of genes near the end of chromosomes by allowing their ends to shorten.
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This could be related to the SF amino acid sequence that acts as cell receptors facilitating cell adhesion and growth.
It's a daring, dizzying, dazzling sequence that acts as pay-off for all those long, languorous scenes across a police interview table.
When the oxygen level returns to normal, the gene switches "off". SRI has secured two patents on the unique DNA sequence that acts as the gene's switch.
It requires a pulse sequence that acts as a null pulse at the solvent-resonance frequency and as an inversion pulse everywhere else.
So the company is using what it calls "micro-dystrophin," a DNA sequence that acts like the full-size gene but is small enough to fit inside a virus.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com