The monolayer allows one side of the nanoparticle to be functionalised with a 20-base oligonucleotide with a C3 spacer thiol (probe) that selectively captures a sequence specifically associated with the strain of Staphylococcus aureus associated with mastitis.
We obtained several DNA sequences that specifically associated with dSETDB1-MBDL but not dSETDB1-MBDL[R436C] dSETDB1-MBDL[R436C]
These ages indicate that the development of the studied talus sequence is not specifically associated with Pleistocene glacial interglacial cycles.
The finding that Hdac1 is stably and specifically associated with sequences within the promoter region and first exon of ascl1b in 12 hpf and 27 hpf zebrafish embryos, transcription of which is Hdac1-dependent throughout this period, identifies ascl1b as a novel in vivo direct target of Hdac1.
Most remarkably, these bidirectional promoters represent a specific promoter category, characterized by its own sequence and epigenetic signature and specifically associated with expression of neuronal genes.
Protein database screening revealed that this domain was specifically associated with APO sequences (data not shown), and spanned amino acids 957 1072 of human apoB.
Notably, several of the candidate enzymes shared significant amino acid sequence identity to CYP450s and esterases specifically associated with pesticide resistance and detoxification.
H3.7, acetylated at lysine-32 (probably equivalent to lysine-36 of most H3 variants), is specifically associated with a sequence class that is retained in the mature macronucleus and therefore does not undergo developmental DNA elimination.
Variations in mtDNA are specifically associated with disease phenotypes with specific sequence alterations in mitochondrial components that may generate measurable effects on bioenergetic and other functional aspects of the organelle, such as a decrease in respiratory function [153].
Perhaps RNAP V-dependent regions are specifically associated with smaller repeat sequences regardless of their repeat class (Fig. 4).
