The initialization method is thus equivalent to finding the best BE model parameters vector that fits, in the LS sense, the transmitted pilot sequence (Note that the noise term in this model is not white (since the data is treated as part of the noise).
I used a sliding window of 50 bp to measure variation in 25-bp steps along the length of the aligned coding sequence (note that because gaps are excluded, the length of the region compared varies among alignments).
At week 40 of what ultimately became an 80-week outbreak, the authors replaced traditional molecular epidemiology methods with whole-genome sequencing, noting that with the less than 1-week turnaround time they achieved with genomics, they were able to more rapidly rule in or rule out isolates as belonging to the outbreak.
Note that sequencing revealed that the pEBG-NEMO K285,309R construct had an additional E287G mutation.
Note that sequences presented in the MSA include all six conserved cysteines (as opposed to four cysteines in PF08087, Fig. 6, bottom).
Note that chimera sequences differ only by the position of the seed, implying that for two subsequent chimeras, a considerable part of the computation is recyclable.
Double-page viewing will scramble the image-text sequence.Please also note that the text pages that follow are not serially paginated.
With K=3, the occurrence number R concerns sequences composed of three applications; we note that the sequence (Spotify, 2048, VLC) appears two times and several other sequences which appear one time.
Re-align sequences within each group and generate a consensus sequence; note that this consensus is different from the PDB representative, to which it nevertheless shares high sequence similarity.
Note that the D3 sequences cover the sequences of D1 or D2, and the A1 sequences cover the ones of A2. (PDF 111 KB).
